Cytokine Signaling Modulates Blood-Brain Barrier Function
نویسندگان
چکیده
منابع مشابه
Adenosine receptor signaling modulates permeability of the blood-brain barrier.
The blood-brain barrier (BBB) is comprised of specialized endothelial cells that form the capillary microvasculature of the CNS and is essential for brain function. It also poses the greatest impediment in the treatment of many CNS diseases because it commonly blocks entry of therapeutic compounds. Here we report that adenosine receptor (AR) signaling modulates BBB permeability in vivo. A(1) an...
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ژورنال
عنوان ژورنال: Current Pharmaceutical Design
سال: 2011
ISSN: 1381-6128
DOI: 10.2174/138161211798220918